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首页 >> 实验室试剂 >> 生命科学 >> Recombinant Human IL-17F Protein
商品参数
  • 所属类别:实验室试剂
  • 产品品牌:阿拉丁
  • 价格区间:2万以上
商品描述


品牌货号


产品名称

阿拉丁rp147435


Recombinant Human IL-17F Protein

别名重组人白介素17F蛋白 | 重组人 IL-17F 蛋白
英文别名Cytokine ML-1 | IL17F | IL-17F | IL-17Finterleukin-17F | interleukin 17F | ML1 | ML-1 | IL17A | CANDF6 | Cytokine ML-1 | IL-17F
规格或纯度ActiBioPure™, Bioactive, Animal Free, Carrier Free, Azide Free, High performance, ≥95%(SDS-PAGE)
产品介绍


Purity
>95% by SDS-PAGE and HPLC analyses.

Function
Ligand for IL17RA and IL17RC (PubMed:17911633). The heterodimer formed by IL17A and IL17F is a ligand for the heterodimeric complex formed by IL17RA and IL17RC (PubMed:18684971). Involved in stimulating the production of other cytokines such as IL6, IL8 and CSF2, and in regulation of cartilage matrix turnover (PubMed:11591732, PubMed:11591768, PubMed:11574464). Also involved in stimulating the proliferation of peripheral blood mononuclear cells and T-cells and in inhibition of angiogenesis (PubMed:11591732). Plays a role in the induction of neutrophilia in the lungs and in the exacerbation of antigen-induced pulmonary allergic inflammation.

生物活性Fully biologically active when compared to standard. The ED50 as determined by inducing IL-6 secretion of murine NIH/3T3 cells is less than 20 ng/ml, corresponding to a specific activity of > 5.0 × 104 IU/mg.
内毒素水平<1.0 EU/μg
表达系统E. coli
种属人(Human)
氨基酸31-163 aa
序列MRKIPKVGHTFFQKPESCPPVPGGSMKLDIGIINENQRVSMSRNIESRSTSPWNYTVTWDPNRYPSEVVQAQCRNLGCINAQGKEDISMNSVPIQQETLVVRRKHQGCSVSFQLEKVLVTVGCTCVTPVIHHVQ
纯度＞95%(SDS-PAGE, HPLC)
蛋白标签No tag
蛋白长度Full length protein
无载体Yes
无动物源Yes
Accession #Q96PD4
来源重组表达
预测分子量30.1 kDa
SDS-PAGE16.4 kDa, under reducing conditions.


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