科学器材商城
购物车0物品
 

欢迎来到探究者科学器材（江苏）有限公司！全国服务热线：4006-765-543

首页 >> 实验室试剂 >> 生物试剂 >> Recombinant Human FGF basic/FGF2/bFGF Protein
商品参数
  • 所属类别:实验室试剂
  • 产品品牌:阿拉丁
  • 价格区间:5000-10000
商品描述


品牌货号


产品名称

阿拉丁rp155946


Recombinant Human FGF basic/FGF2/bFGF Protein

别名重组人FGF basic/FGF2/bFGF蛋白 | 重组人碱性成纤维细胞生长因子蛋白 | 植物源重组人碱性成纤维细胞生长因子
英文别名basic fibroblast growth factor bFGF | Basic fibroblast growth factor | bFGF | FGF basic | FGF2 | FGF-2 | FGFBprostatropin | fibroblast growth factor 2 (basic) | HBGF-2 | heparin-binding growth factor 2 | Prostatropin
规格或纯度无载体, GMP, 生物活性, ActiBioPure™, 高性能, 无动物源, ≥95%(SDS-PAGE)
生化机理Acts as a ligand for FGFR1, FGFR2, FGFR3 and FGFR4. Also acts as an integrin ligand which is required for FGF2 signaling. Binds to integrin ITGAV:ITGB3. Plays an important role in the regulation of cell survival, cell division, cell differentiation and cell migration. Functions as a potent mitogen in vitro. Can induce angiogenesis. Mediates phosphorylation of ERK1/2 and thereby promotes retinal lens fiber differentiation. Post-translational: Phosphorylation at Tyr-215 regulates FGF2 unconventional secretion. Several N-termini starting at positions 94, 125, 126, 132, 143 and 162 have been identified by direct sequencing.
产品介绍

碱性成纤维细胞生长因子（bFGF，FGF2或FGF-β）是成纤维细胞生长因子家族中的一员。bFGF是一种单链多肽生长因子，在促进细胞增殖过程中起着重要作用；同时也可以抑制细胞凋亡，加速伤口愈合并诱导血管再生。在中胚层和神经外胚层等多种类型的细胞中，bFGF亦能非常有效地诱导DNA的合成。OsrhbFGF是运用基因重组技术，由水稻胚乳细胞表达并通过蛋白提纯工艺而成。

Basic fibroblast growth factor (bFGF, FGF2 or FGF-β) is a member of the fibroblast growth factor family. bFGF is a kind of single-chain polypeptide growth factor, which plays an important role in promoting cell proliferation. It can also inhibit cell apoptosis, accelerate wound healing and induce blood vessel regeneration. In many cell types, such as mesoderm and neuroectoderm, bFGF is also very effective in inducing DNA synthesis. OsrhbFGF is expressed by rice endosperm cells and purified by gene recombination technology.

生物活性Measured in a cell proliferation assay using BALB/3T3 mouse embryo fibroblasts cell line. The ED₅₀ for this effect is typically <1 ng/mL.
内毒素水平<1.0 EU/μg
表达系统水稻
种属人(Human)
氨基酸134-288 aa
序列MAAGSITTLPALPEDGGSGAFPPGHFKDPKRLYCKNGGFFLRIHPDGRVDGVREKSDPHIKLQLQAEERGVVSIKGVCANRYLAMKEDGRLLASKCVTDECFFFERLESNNYNTYRSRKYTSWYVALKRTGQYKLGSKTGPGQKAILFLPMSAKS
纯度≥95% (SDS-PAGE)
蛋白标签No tag
蛋白长度Full length protein
无载体Yes
Accession #P09038
来源重组表达
预测分子量17 kDa


  • 购买人 会员级别 数量 属性 购买时间
    • 总计 0 条记录
  • 商品满意度 ：
暂无评价信息
备注：无质量问题不做退换货处理，下单前请仔细确认，感谢配合！