品牌货号 产品名称 | 阿拉丁rp145392 Recombinant Human EGF Protein |
---|---|
别名 | 重组人表皮生长因子(EGF) | 重组人表皮生长因子蛋白 | 重组人EGF蛋白 |
英文别名 | beta-urogastrone | EGF | epidermal growth factor (beta-urogastrone) | epidermal growth factor | hEGF | HOMG4 | pro-epidermal growth factor | URG | Urogastrone | EGF |
规格或纯度 | 无载体, GMP, 生物活性, ActiBioPure™, 高性能, 无动物源, ≥95%(SDS-PAGE) |
生化机理 | EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. Can induce neurite outgrowth in motoneurons of the pond snail Lymnaea stagnalis in vitro. Post-translational: O-glycosylated with core 1-like and core 2-like glycans. It is uncertain if Ser-954 or Thr-955 is O-glycosylated. The modification here shows glycan heterogeneity: HexHexNAc (major) and Hex2HexNAc2 (minor). |
生物活性 | Measured in a cell proliferation assay using BALB/3T3 mouse embryo fibroblasts cell line. The ED₅₀ for this effect is typically <0.9 ng/mL. |
内毒素水平 | <0.2 EU/μg |
表达系统 | 毕赤酵母 |
种属 | 人(Human) |
氨基酸 | 971-1021 aa |
序列 | NSDSECPLSHDGYCLHDGVCMYIEALDKYACNCVVGYIGERCQYRDLKWWE |
纯度 | >95% SDS-PAGE |
蛋白标签 | No tag |
蛋白长度 | Full length protein |
无载体 | Yes |
Accession # | P01133 |
来源 | 重组表达 |
预测分子量 | 6 kDa |
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