科学器材商城

欢迎来到探究者科学器材(江苏)有限公司!全国服务热线:4006-765-543

  • Recombinant Human EGF Protein
    ❤ 收藏
  • Recombinant Human EGF Protein

    实验室试剂
    阿拉丁
    2000-5000
    • ¥339.90-4099.90
      ¥0.00
      ¥339.90-4099.90
      ¥203.94-2459.94
    • 满意度:

      销量: 0

      评论: 0 次

    重量:0.00KG
    • 数量:
商品参数
  • 所属类别:实验室试剂
  • 产品品牌:阿拉丁
  • 价格区间:2000-5000
商品描述


品牌货号


产品名称

阿拉丁rp185510


Recombinant Human EGF Protein

别名重组人表皮生长因子 | 重组人EGF | 重组人EGF蛋白
英文别名Recombinant Human Epidermal Growth Factor | rhEGF | beta-urogastrone | EGF | epidermal growth factor (beta-urogastrone | epidermal growth factor | hEGF | HOMG4 | pro-epidermal growth factor | URG | Urogastrone
规格或纯度ActiBioPure™, Bioactive, GMP, Carrier Free, Azide Free, High performance, ≥95%(SDS-PAGE)
产品介绍

pH值:6.5-7.5

人表皮生长因子(EGF)分子量为6.5kD,含有53个氨基酸,分子内有3个二硫键。EGF与位于细胞表面的特异受体EGFR 结合后,引起细胞内一系列的生化反应:提高细胞内的钙离子浓度水平,促进糖酵解的进行,增加蛋白质的合成,并且可以增强EGFR这一类特定基因的表达来促进DNA 的合成和细胞的增殖。

Purity

≥95% SDS-PAGE

Additional sequence information

Mature chain

Function

EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. Can induce neurite outgrowth in motoneurons of the pond snail Lymnaea stagnalis in vitro (PubMed:10964941).

Post-translational

O-glycosylated with core 1-like and core 2-like glycans. It is uncertain if Ser-954 or Thr-955 is O-glycosylated. The modification here shows glycan heterogeneity: HexHexNAc (major) and Hex2HexNAc2 (minor).

pH value: 6.5-7.5

Human epidermal cell growth factor, Mannitol, Sodium dihydrogen monohydrate phosphate, Disodium hydrogen dodecahydrate phosphate, Water 
生物活性Measured in a cell proliferation assay using BALB/3T3 mouse embryo fibroblasts cell line. The ED₅₀ for this effect is typically <1 ng/mL.
内毒素水平<0.01 EU/μg
表达系统毕赤酵母
种属人(Human)
氨基酸971-1023 aa
序列NSDSECPLSH DGYCLHDGVC MYIEALDKYA CNCVVGYIGE RCQYRDLKWW ELR
蛋白标签No tag
无载体Yes
Accession #P01133
来源重组表达
预测分子量6.5kD
SDS-PAGE7.1 kDa, under reducing conditions.


  • 购买人 会员级别 数量 属性 购买时间
  • 商品满意度 :
暂无评价信息
备注:无质量问题不做退换货处理,下单前请仔细确认,感谢配合!