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首页 >> 实验室试剂 >> 生物试剂 >> Recombinant Human BDNF GMP Protein
  • Recombinant Human BDNF GMP Protein
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  • Recombinant Human BDNF GMP Protein

    实验室试剂
    阿拉丁
    2万以上
    • ￥2399.90-26999.90
      ￥0.00
      ￥2399.90-26999.90
      ￥1439.94-16199.94

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  • 所属类别:实验室试剂
  • 产品品牌:阿拉丁
  • 价格区间:2万以上
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阿拉丁rp143209


Recombinant Human BDNF GMP Protein

别名重组人BDNF蛋白 | 重组人脑源性神经营养因子蛋白 | 重组人 BDNF GMP 蛋白 | 重组人BDNF蛋白 | 重组人脑源性神经营养因子蛋白
英文别名Abrineurin | BDNF | Abrineurin | ANON2 | BDNF | brain-derived neurotrophic factor | BULN2 | MGC34632 | Neurotrophin | Abrineurin | ANON2 | BDNF | brain-derived neurotrophic factor | BULN2 | MGC34632 | Neurotrophin
规格或纯度无动物源, Carrier Free, GMP, 生物活性, ActiBioPure™, High performance, ≥97%(SDS-PAGE&SEC-HPLC)
生化机理Important signaling molecule that activates signaling cascades downstream of NTRK2. During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including long-term potentiation (LTP), long-term depression (LTD), certain forms of short-term synaptic plasticity, as well as homeostatic regulation of intrinsic neuronal excitability.
生物活性Measured in a cell proliferation assay using BaF mouse pro-B cells transfected with TrkB. The ED50 for this effect is 0.100-1.00 ng/mL. The specific activity of Recombinant Human BDNF is >8.0 x 10^5 units/mg, which is calibrated against the human BDNF WHO Standard (NIBSC code: 96/534).
内毒素水平<0.1 EU/μg
表达系统E. coli
种属人(Human)
氨基酸134-247 aa
序列MRRGELSVCDSISEWVTAADKKTAVDMSGGTVTVLEKVPVSKGQLKQYFYETKCNPMGYTKEGCRGIDKRHWNSQCRTTQSYVRALTMDSKKRIGWRFIRIDTSCVCTLTIKRGR
蛋白标签No tag
N-末端序列Met-Arg134-Arg-Gly-Glu-Leu-Ser-Val-(Cys)-Asp
无载体Yes
无动物源Yes
Accession #P23560
来源重组表达
预测分子量13.1 kDa
SDS-PAGE12 kDa, under reducing conditions.


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