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首页 >> 实验室试剂 >> 生命科学 >> Recombinant Mouse Leptin Protein
  • Recombinant Mouse Leptin Protein
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  • Recombinant Mouse Leptin Protein

    实验室试剂
    阿拉丁
    2000-5000
    • ￥2999.90
      ￥0.00
      ￥2999.90
      ￥1799.94

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  • 所属类别:实验室试剂
  • 产品品牌:阿拉丁
  • 价格区间:2000-5000
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产品名称

阿拉丁L329647-


Recombinant Mouse Leptin Protein

别名重组小鼠Leptin蛋白 | 重组小鼠瘦素蛋白
英文别名FLJ94114 | LEP | leptin (murine obesity homolog) | leptin (obesity homolog, mouse) | Leptin | OB | Obese protein | obese, mouse, homolog of | Obesity factor | OBOBS | obese
规格或纯度ActiBioPure™, 生物活性, 无动物源, 无载体, ≥95%(SDS-PAGE)
生化机理May function as part of a signaling pathway that acts to regulate the size of the body fat depot. An increase in the level of LEP may act directly or indirectly on the CNS to inhibit food intake and/or regulate energy expenditure as part of a homeostatic mechanism to maintain constancy of the adipose mass. Leptin, known as the "satiety hormone", is a hormone made by adipose cells that helps to regulate energy balance by inhibiting hunger. Leptin is opposed by the actions of the hormone ghrelin, the "hunger hormone". Both hormones act on receptors in the arcuate nucleus of the hypothalamus to regulate appetite in order to achieve energy homeostasis. In obesity, a decreased sensitivity to leptin occurs, resulting in an inability to detect satiety despite high energy stores.
生物活性Immobilized Recombinant Mouse LEPR (C-10His) at 5μg/ml (100 μl/well) can bind Recombinant Mouse Leptin Biotinylated by NHS-biotin prior to testing.The ED50 of Recombinant Mouse Leptin is 1.16 ng/ml. Loaded Recombinant Mouse LEPR (C-10His) on HIS1K Biosensor, can bind Recombinant Mouse Leptin with an affinity constant of 0.196 nM as determined in BLI assay.
内毒素水平<1.0 EU/μg
表达系统E. coli
种属小鼠(Mouse)
氨基酸22-167 aa
序列VPIQKVQDDTKTLIKTIVTRINDISHTQSVSAKQRVTGLDFIPGLHPILSLSKMDQTLAVYQQVLTSLPSQNVLQIANDLENLRDLLHLLAFSKSCSLPQTSGLQKPESLDGVLEASLYSTEVVALSRLQGSLQDILQQLDVSPEC
蛋白标签No tag
无载体Yes
无动物源Yes
Accession #Q544U0
来源重组表达
预测分子量16.1 KDa
SDS-PAGE14 KDa, under reducing conditions.


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