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首页 >> 实验室试剂 >> 检测试剂 >> Mouse FcR Blocking Reagent
  • Mouse FcR Blocking Reagent
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  • Mouse FcR Blocking Reagent

    实验室试剂
    阿拉丁
    0-2000
    • ￥199.90-1599.90
      ￥0.00
      ￥199.90-1599.90
      ￥119.94-959.94

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  • 所属类别:实验室试剂
  • 产品品牌:阿拉丁
  • 价格区间:0-2000
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产品名称

阿拉丁Ab219990


Mouse FcR Blocking Reagent

别名Fc受体阻断剂 | Fc受体封闭剂 | FcR阻断剂 | 小鼠Fc受体封闭剂 | FcγIII受体 | FcγII受体 | 白细胞分化抗原16 | 白细胞分化抗原32 | CD16/32抗体
英文别名Fc block | Fc Receptor Blocker | FcR Blocking Reagent, mouse | Mouse Fc blocker | Fc receptor blocking antibody | Mouse Fc Receptor Blocking Solution | Fc Receptor Binding Inhibitor Antibody | anti-Mouse Fc Block Monoclonal Antibody | Fc Receptor Blocking
规格或纯度重组, 无叠氮钠, 已验证, 高性能, ≥95%(SDS-PAGE), 0.2 mg/mL
生化机理CD16: Receptor for the Fc region of complexed immunoglobulins gamma. Low affinity receptor which binds to IgG1, IgG2a and IgG2b. Mediates neutrophil activation by IgG complexes redundantly with Fcgr4. CD32: Receptor for the Fc region of complexed immunoglobulins gamma. Low affinity receptor. Involved in a variety of effector and regulatory functions such as phagocytosis of antigen-antibody complexes from the circulation and modulation of antibody production by B-cells. Isoform IIB1 and isoform IIB1' form caps but fail to mediate endocytosis or phagocytosis. Isoform IIB2 can mediate the endocytosis of soluble immune complexes via clathrin-coated pits. Isoform IIB1 and isoform IIB2 can down-regulate B-cell, T-cell, and mast cell activation when coaggregated to B-cell receptors for AG (BCR), T-cell receptors for AG (TCR), and Fc receptors, respectively.
宿主种属大鼠(Rat)
特异性Mouse CD16/CD32
种属反应性小鼠(Mouse)
免疫原Mouse BALB/c Macrophage J774
阳性对照Flow Cytometry: C57BL/6 mouse splenocytes
偶联Unconjugated


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