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商品参数
  • 所属类别:实验室试剂
  • 产品品牌:阿拉丁
  • 价格区间:2万以上
商品描述


品牌货号



产品名称

阿拉丁rp152513



Recombinant Human TNFRSF1A Protein

别名重组人TNFRSF1A蛋白 | 重组人 TNFRSF1A 蛋白
英文别名CD120a antigen | CD120a | FPF | p55 | p55-R | p60 | TNF RI | TNFARMGC19588 | TNF-R | TNF-R1 | TNFR1TBP1 | TNFR55 | TNF-R55 | TNFR60 | TNFRI | TNF-RI | TNF-R-I | TNFR-I | TNFRSF1A | tumor necrosis factor binding protein 1 | Tumor necrosis factor receptor 1
规格或纯度ActiBioPure™, Bioactive, Animal Free, Carrier Free, Azide Free, High performance, ≥97%(SDS-PAGE&HPLC)
产品介绍


Purity

> 97 % by SDS-PAGE and HPLC analyses.


Function

Receptor for TNFSF2/TNF-alpha and homotrimeric TNFSF1/lymphotoxin-alpha. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Contributes to the induction of non-cytocidal TNF effects including anti-viral state and activation of the acid sphingomyelinase.

生物活性Fully biologically active when compared to standard. The ED₅₀ as determined by its ability to inhibit the TNF-alpha mediated cytotoxicity in the L-929 cells is less than 0.05 μg/ml in the presence of 0.25 ng/mL of rHuTNF-alpha.
内毒素水平<0.1 EU/μg
表达系统E. coli
种属人(Human)
氨基酸22-211 aa
序列IYPSGVIGLV PHLGDREKRD SVCPQGKYIH PQNNSICCTK CHKGTYLYND CPGPGQDTDC RECESGSFTA SENHLRHCLS CSKCRKEMGQ VEISSCTVDR DTVCGCRKNQ YRHYWSENLF QCFNCSLCLN GTVHLSCQEK QNTVCTCHAG FFLRENECVS CSNCKKSLEC TKLCLPQIEN VKGTEDSGTT
纯度>97%(SDS-PAGE, HPLC)
蛋白标签No tag
蛋白长度Protein fragment
无载体Yes
无动物源Yes
Accession #P19438
来源重组表达
预测分子量21.2 kDa



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