品牌货号 产品名称 | 阿拉丁rp152513 Recombinant Human TNFRSF1A Protein |
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别名 | 重组人TNFRSF1A蛋白 | 重组人 TNFRSF1A 蛋白 |
英文别名 | CD120a antigen | CD120a | FPF | p55 | p55-R | p60 | TNF RI | TNFARMGC19588 | TNF-R | TNF-R1 | TNFR1TBP1 | TNFR55 | TNF-R55 | TNFR60 | TNFRI | TNF-RI | TNF-R-I | TNFR-I | TNFRSF1A | tumor necrosis factor binding protein 1 | Tumor necrosis factor receptor 1 |
规格或纯度 | ActiBioPure™, Bioactive, Animal Free, Carrier Free, Azide Free, High performance, ≥97%(SDS-PAGE&HPLC) |
产品介绍 | Purity > 97 % by SDS-PAGE and HPLC analyses. Function Receptor for TNFSF2/TNF-alpha and homotrimeric TNFSF1/lymphotoxin-alpha. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Contributes to the induction of non-cytocidal TNF effects including anti-viral state and activation of the acid sphingomyelinase. |
生物活性 | Fully biologically active when compared to standard. The ED₅₀ as determined by its ability to inhibit the TNF-alpha mediated cytotoxicity in the L-929 cells is less than 0.05 μg/ml in the presence of 0.25 ng/mL of rHuTNF-alpha. |
内毒素水平 | <0.1 EU/μg |
表达系统 | E. coli |
种属 | 人(Human) |
氨基酸 | 22-211 aa |
序列 | IYPSGVIGLV PHLGDREKRD SVCPQGKYIH PQNNSICCTK CHKGTYLYND CPGPGQDTDC RECESGSFTA SENHLRHCLS CSKCRKEMGQ VEISSCTVDR DTVCGCRKNQ YRHYWSENLF QCFNCSLCLN GTVHLSCQEK QNTVCTCHAG FFLRENECVS CSNCKKSLEC TKLCLPQIEN VKGTEDSGTT |
纯度 | >97%(SDS-PAGE, HPLC) |
蛋白标签 | No tag |
蛋白长度 | Protein fragment |
无载体 | Yes |
无动物源 | Yes |
Accession # | P19438 |
来源 | 重组表达 |
预测分子量 | 21.2 kDa |
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