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商品参数
  • 所属类别:实验室试剂
  • 产品品牌:阿拉丁
  • 价格区间:1万以上
商品描述


品牌货号


产品名称

阿拉丁Ab112020


Ki67 Mouse mAb

别名增殖标志物Ki67抗体 | 增殖标志物Ki67单克隆抗体 | 增殖标志物Ki67组化抗体 | MKI67抗体 | MKI67单克隆抗体 | MKI67组化抗体
英文别名Antigen identified by monoclonal antibody Ki 67 antibody | Antigen identified by monoclonal antibody Ki-67 antibody | Antigen KI-67 antibody | Antigen KI67 antibody | KI67_HUMAN antibody | KIA antibody | Marker of proliferation Ki-67 antibody | MIB 1 anti
规格或纯度无载体, ExactAb™, 无叠氮钠, 已验证, 见COA
生化机理Required to maintain individual mitotic chromosomes dispersed in the cytoplasm following nuclear envelope disassembly. Associates with the surface of the mitotic chromosome, the perichromosomal layer, and covers a substantial fraction of the chromosome surface. Prevents chromosomes from collapsing into a single chromatin mass by forming a steric and electrostatic charge barrier: the protein has a high net electrical charge and acts as a surfactant, dispersing chromosomes and enabling independent chromosome motility. Binds DNA, with a preference for supercoiled DNA and AT-rich DNA. Does not contribute to the internal structure of mitotic chromosomes (By similarity). May play a role in chromatin organization. It is however unclear whether it plays a direct role in chromatin organization or whether it is an indirect consequence of its function in maintaining mitotic chromosomes dispersed.
宿主种属小鼠(Mouse)
特异性Ki67
种属反应性人(Human)
免疫原Peptide
阳性对照IHC: Human tonsil tissue.
偶联Unconjugated


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