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首页 >> 实验室试剂 >> 生命科学 >> Recombinant mouse IL-7 protein
商品参数
  • 所属类别:实验室试剂
  • 产品品牌:阿拉丁
  • 价格区间:2万以上
商品描述


品牌货号


产品名称

阿拉丁rp154245


Recombinant mouse IL-7 protein

别名重组小鼠白细胞介素7蛋白 | 重组小鼠 IL-7 蛋白
英文别名IL7 | IL-7 | interleukin-7 | interleukin 7 | Lymphopoietin-1 | PBGF | hlb368 | A630026I06Rik
规格或纯度ActiBioPure™, Bioactive, Animal Free, Carrier Free, Azide Free, High performance, ≥97%(SDS-PAGE)
产品介绍


Purity

>97% SDS-PAGE.


Interleukin-7 (IL-7) is encoded by the IL7 gene in mouse and secreted by stromal cells in the red marrow and thymus. The protein signals through the IL-7 receptor, which is a heterodimer consisting of IL-7 receptor alpha and IL-2 receptor gamma chain. IL-7 stimulates the differentiation of hematopoietic stem cells into lymphoid progenitor cells and it can stimulate proliferation of B cells, T cells and NK cells. Mouse IL-7 has approximately 65 % and 88 % amino acid sequence identity with human and rat IL-7 and both proteins exhibit cross-species activity. Recombinant Mouse IL-7 is a 14.9kDa globular protein containing 129 amino acid residues.


Function

Hematopoietic growth factor capable of stimulating the proliferation of lymphoid progenitors. It is important for proliferation during certain stages of B-cell maturation.

生物活性Measured in a cell proliferation assay using PHA-activated human peripheral blood mononuclear cell (PBMC). The ED50 for this effect is less than 1ng/mL。
内毒素水平<0.01 EU/μg
表达系统E. coli
种属小鼠(Mouse)
氨基酸26-154 aa
序列ECHIKDKEGKAYESVLMISIDELDKMTGTDSNCPNNEPNFFRKHVCDDTKEAAFLNRAARKLKQFLKMNISEEFNVHLLTVSQGTQTLVNCTSKEEKNVKEQKKNDACFLKRLLREIKTCWNKILKGSI
纯度＞97%(SDS-PAGE)
蛋白标签No tag
N-末端序列Glu-Cys-His-Ile-Lys-Asp-Lys-Glu
蛋白长度Full length protein
无载体Yes
无动物源Yes
Accession #Q544C8
来源重组表达
预测分子量14.9 kDa
SDS-PAGE12.9 kDa, under reducing conditions; 12.1 kDa, under non-reducing conditions.



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