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  • Recombinant Human IFN-alpha-2B Protein
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  • Recombinant Human IFN-alpha-2B Protein

    实验室试剂
    阿拉丁
    2万以上
    • ¥499.90
      ¥0.00
      ¥499.90
      ¥299.94
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  • 所属类别:实验室试剂
  • 产品品牌:阿拉丁
  • 价格区间:2万以上
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品牌货号


产品名称

阿拉丁rp156087


Recombinant Human IFN-alpha-2B Protein

别名重组人 IFN-alpha-2B 蛋白
英文别名IFN-alpha-2 | Interferon alpha-A | LeIF A
规格或纯度无动物源, Carrier Free, 生物活性, ActiBioPure™, ≥98%(SDS-PAGE&HPLC)
产品介绍

干扰素(IFN)以其在宿主防御机制中的关键作用而闻名。Ⅰ型干扰素包括IFN-alpha 家族,IFN-beta, -omega,-kappa 和 Limitin/IFN-zeta,对调节病毒感染的免疫应答具有重要意义。Ⅱ型干扰素组仅包括干扰素γ。IFN-γ是一种多功能细胞因子,具有抗增殖、免疫调节和促炎症作用,对免疫应答的许多方面都很重要。Ⅲ型干扰素家族包括IL-29/IFN-lambda 1, IL-28A/IFN-lambda 2, IL-28B/IFN-lambda 3, and IFN-lambda 4。与Ⅰ型干扰素类似,Ⅲ型干扰素具有抗病毒、抗增殖和免疫调节作用。

IFN-αs are proteins secreted by leukocyte. They are mainly involved in innate immune response against viral infection. The IFN-α family has 13 subtypes and 23 different variants. The individual proteins have molecular masses between 19-26 kDa and consist of proteins with lengths of 156-166 and 172 amino acids. All IFN-α subtypes possess a common conserved sequence region between amino acid positions 115-151 while the amino-terminal ends are variable. Many IFN-alpha subtypes differ in their sequences at only one or two positions. Naturally occurring variants also include proteins truncated by 10 amino acids at the carboxy-terminal end.

生物活性Fully biologically active when compared to standard. The specific activity determined by an anti-viral assay is no less than 1.6 × 10^8 IU/mg.
内毒素水平<0.1 EU/μg
表达系统酵母
种属人(Human)
氨基酸24-188 aa
序列CDLPQTHSLG SRRTLMLLAQ MRRISLFSCL KDRHDFGFPQ EEFGNQFQKA ETIPVLHEMI QQIFNLFSTK DSSAAWDETL LDKFYTELYQ QLNDLEACVI QGVGVTETPL MKEDSILAVR KYFQRITLYL KEKKYSPCAW EVVRAEIMRS FSLSTNLQES LRSKE
纯度>98% ( SDS-PAGE and HPLC)
蛋白标签No tag
蛋白长度Full length protein
无载体Yes
无动物源Yes
Accession #P01563
来源重组表达
预测分子量19.3 kDa


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