品牌货号 产品名称 | 阿拉丁rp143727 Recombinant Human CCL14 Protein |
---|---|
别名 | 重组人CCL14蛋白 | 重组人CCL14蛋白 |
英文别名 | CC-1 | CC-3 | CCL14 | CCL14_HUMAN | chemokine (C-C motif) ligand 14 | Chemokine CC-1/CC-3 | chemokine CC1 | chemokine CC3 | chemokine HCC1 | chemokine HCC3 | CKb1 | HCC 1 | HCC 3 | HCC-1(1-74) | HCC-1(9-74) | HCC-1/HCC-3 | HCC-3 | HCC1 | HEMOFILTRATE CC C |
规格或纯度 | ActiBioPure™, Bioactive, Animal Free, Carrier Free, Azide Free, High performance, ≥96%(SDS-PAGE&HPLC) |
产品介绍 | Purity > 96% by SDS-PAGE and HPLC analyses. Function Has weak activities on human monocytes and acts via receptors that also recognize MIP-1 alpha. It induced intracellular Ca(2+) changes and enzyme release, but no chemotaxis, at concentrations of 100-1,000 nM, and was inactive on T-lymphocytes, neutrophils, and eosinophil leukocytes. Enhances the proliferation of CD34 myeloid progenitor cells. The processed form HCC-1(9-74) is a chemotactic factor that attracts monocytes eosinophils, and T-cells and is a ligand for CCR1, CCR3 and CCR5. Post-translational The N-terminal processed forms HCC-1(3-74), HCC-1(4-74) and HCC-1(9-74) are produced in small amounts by proteolytic cleavage after secretion in blood. HCC-1(1-74), but not HCC-1(3-74) and HCC-1(4-74), is partially O-glycosylated; the O-linked glycan consists of one Gal-GalNAc disaccharide, further modified by two N-acetylneuraminic acids. |
生物活性 | Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using human monocytes is in a concentration of 5.0-20 ng/ml. |
内毒素水平 | <1.0 EU/μg |
表达系统 | E. coli |
种属 | 人(Human) |
氨基酸 | 22-93 aa |
序列 | TESSSRGPYH PSECCFTYTT YKIPRQRIMD YYETNSQCSK PGIVFITKRG HSVCTNPSDK WVQDYIKDMK EN |
纯度 | >96%(SDS-PAGE and HPLC) |
蛋白标签 | No tag |
蛋白长度 | Full length protein |
无载体 | Yes |
无动物源 | Yes |
Accession # | Q16627 |
来源 | 重组表达 |
预测分子量 | 8.4 kDa |
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