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商品参数
  • 所属类别:实验室试剂
  • 产品品牌:阿拉丁
  • 价格区间:2万以上
商品描述


品牌货号


产品名称

阿拉丁rp150860


Recombinant Human RANTES Protein

别名重组人RANTES蛋白 | 重组人类RANTES蛋白
英文别名CCL5 | chemokine (C-C motif) ligand 5 | D17S136Enormally T-expressed, and presumably secreted | EoCP | Eosinophil chemotactic cytokine | RANTES | SISd | SIS-delta | small inducible cytokine A5 (RANTES) | small inducible cytokine subfamily A (Cys-Cys), mem
规格或纯度ActiBioPure™, Bioactive, Animal Free, Carrier Free, Azide Free, High performance, ≥98%(SDS-PAGE&HPLC)
产品介绍


Purity
>98% by SDS-PAGE and HPLC analyses.

Function
Chemoattractant for blood monocytes, memory T-helper cells and eosinophils. Causes the release of histamine from basophils and activates eosinophils. Binds to CCR1, CCR3, CCR4 and CCR5. One of the major HIV-suppressive factors produced by CD8+ T-cells. Recombinant RANTES protein induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV). The processed form RANTES(3-68) acts as a natural chemotaxis inhibitor and is a more potent inhibitor of HIV-1-infection. The second processed form RANTES(4-68) exhibits reduced chemotactic and HIV-suppressive activity compared with RANTES(1-68) and RANTES(3-68) and is generated by an unidentified enzyme associated with monocytes and neutrophils.

生物活性Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using human peripheral blood monocytes is in a concentration range of 1.0-10 ng/ml.
内毒素水平<1.0 EU/μg
表达系统E. coli
种属人(Human)
氨基酸24-91 aa
序列SPYSSDTTPCCFAYIARPLPRAHIKEYFYTSGKCSNPAVVFVTRKNRQVCANPEKKWVREYINSLEMS
纯度>98%(SDS-PAGE, HPLC)
蛋白标签No tag
蛋白长度Full length protein
无载体Yes
无动物源Yes
Accession #P13501
来源重组表达
预测分子量7.8 kDa
SDS-PAGE7.8 kDa


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