品牌货号 产品名称 | 阿拉丁rp147252 Recombinant Human IGF-1 Protein |
---|---|
别名 | 重组人IGF-1蛋白 | 重组人胰岛素样生长因子1蛋白 |
英文别名 | IGF-I | Mechano growth factor | MGF | Somatomedin-C |
规格或纯度 | 无动物源, 无载体, 生物活性, ActiBioPure™, 高性能, GMP, ≥95%(SDS-PAGE) |
生化机理 | The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity. May be a physiological regulator of [1-14C]-2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblasts. Stimulates glucose transport in rat bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also with regard to enhancing glucose uptake. |
产品介绍 | |
生物活性 | Measured in a cell proliferation assay using MCF7 breast cancer cell line. The ED₅₀ for this effect is typically <4.6 ng/mL. |
内毒素水平 | <0.2 EU/μg |
表达系统 | 毕赤酵母 |
种属 | 人(Human) |
氨基酸 | 49-118 aa |
序列 | GP ETLCGAELVD ALQFVCGDRG FYFNKPTGYG SSSRRAPQTG IVDECCFRSC DLRRLEMYCA PLKPAKSA |
纯度 | >95% SDS-PAGE |
蛋白标签 | No tag |
N-末端序列 | Gly |
蛋白长度 | Full length protein |
无载体 | Yes |
无动物源 | Yes |
Accession # | P05019 |
来源 | 重组表达 |
预测分子量 | 7.7 kDa |
SDS-PAGE | 8.5 kDa, under reducing conditions; 8.5 kDa, under non-reducing conditions. |
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