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商品参数
  • 所属类别:实验室试剂
  • 产品品牌:阿拉丁
  • 价格区间:1万以上
商品描述


品牌货号


产品名称

阿拉丁rp156680


Recombinant Human Aurora B Protein

别名重组人Aurora B/AIM1蛋白 | 重组人 Aurora B 蛋白
英文别名AIK2AIM-1 | AIM1 | ARK-2 | ARK2 | AurB | AURKB | AURKB_HUMAN | Aurora 1 | Aurora and Ipl1 like midbody associated protein 1 | Aurora kinase B | Aurora related kinase 2 | Aurora- and Ipl1-like midbody-associated protein 1 | Aurora-B | Aurora-related kinase
规格或纯度Carrier Free, Azide Free, ≥90%(SDS-PAGE)
产品介绍


Purity:>90%, by SDS-PAGE visualized with Coomassie® Blue Staining.
Description:
Aurora-B, previously known as AIM-1, is a conserved eukaryotic mitotic protein kinase. In mammals, this kinase plays an essential role in chromosomal segregation processes, including chromosome condensation, alignment, control of spindle checkpoints, chromosome segregation, and cytokinesis. Aurora-B is overexpressed in various cancer cells, suggesting that the kinase activity perturbs chromosomal segregation processes. Its forced overexpression induces chromosomal number instability and progressive tumorigenicity in rodent cells in vitro and in vivo.

内毒素水平<1.0 EU/μg
表达系统E. coli
种属人(Human)
氨基酸1-344 aa


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