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商品参数
  • 所属类别:实验室试剂
  • 产品品牌:阿拉丁
  • 价格区间:1万以上
商品描述


品牌货号


产品名称

阿拉丁rp142510


Recombinant Human Activin RIIA Protein

别名激活素A受体ⅡA(ACVR2A)重组蛋白 | 重组人类激活素 RIIA 蛋白
英文别名Activin receptor type IIA | ACTRIIA | ACTR-IIA | EC 2.7.11.30 | Activin A receptor type IIA | Activin receptor type 2A | Activin receptor type IIA | Activin receptor type-2A | ACTR 2 | ACTR IIA | ACTR-IIA | ACTR2 | ACTRII | ACTRIIA | Acvr 2A | Acvr 2 | Ac
规格或纯度ActiBioPure™, Bioactive, Animal Free, Carrier Free, Azide Free, High performance, ≥95%(SDS-PAGE)
产品介绍


Purity
≥95% (SDS-PAGE)
Endotoxin level
<0.1 EU/μg
Function
On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for activin A, activin B and inhibin A.

生物活性Measured by its ability to inhibit Activin A-induced hemoglobin expression in K562 human chronic myelogenous leukemia cells. Approximately 0.01-0.05 μg/mL of Recombinant Human (rh) Activin RIIA Fc Chimera will inhibit 50% of the biological response due to 3 ng/mL of rhActivin A.
内毒素水平<0.1 EU/μg
表达系统HEK293


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