科学器材商城
购物车0物品
 

欢迎来到探究者科学器材（江苏）有限公司！全国服务热线：4006-765-543

首页 >> 实验室试剂 >> 生命科学 >> Recombinant Human Frizzled-9 Protein
商品参数
  • 所属类别:实验室试剂
  • 产品品牌:阿拉丁
  • 价格区间:1万以上
商品描述


品牌货号


产品名称

阿拉丁rp165192


Recombinant Human Frizzled-9 Protein

别名卷曲同源物9(FZD9)重组蛋白
英文别名CD349 antigen | CD349 | frizzled (Drosophila) homolog 9 | frizzled homolog 9 (Drosophila) | Frizzled9 | Frizzled-9 | fz-9 | FZD3 | fzE6 | FZD9 | hFz9
规格或纯度ActiBioPure™, 生物活性, 无动物源, Carrier Free, ≥90%(SDS-PAGE)
产品介绍


Function
Receptor for Wnt proteins. Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. A second signaling pathway involving PKC and calcium fluxes has been seen for some family members, but it is not yet clear if it represents a distinct pathway or if it can be integrated in the canonical pathway, as PKC seems to be required for Wnt-mediated inactivation of GSK-3 kinase. Both pathways seem to involve interactions with G-proteins. May be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues.

生物活性Measured by its ability to bind biotinylated recombinant mouse Wnt-3a in a functional ELISA with an ED50 of 15-90 ng/mL.
内毒素水平<0.1 EU/μg
表达系统HEK293
种属人(Human)
氨基酸23-185 aa


  • 购买人 会员级别 数量 属性 购买时间
    • 总计 0 条记录
  • 商品满意度 ：
暂无评价信息
备注：无质量问题不做退换货处理，下单前请仔细确认，感谢配合！