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首页 >> 实验室试剂 >> 生命科学 >> Recombinant Human Cathepsin S Protein
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  • 所属类别:实验室试剂
  • 产品品牌:阿拉丁
  • 价格区间:1万以上
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产品名称

阿拉丁rp181600


Recombinant Human Cathepsin S Protein

别名重组人Cathepsin S蛋白 | 重组人组织蛋白酶S
英文别名Cathepsin S | CTSS | EC 3.4.22 | EC 3.4.22.27 | FLJ50259 | MGC3886
规格或纯度无动物源, 无载体, ActiBioPure™, 生物活性, ≥90%(SDS-PAGE)
生化机理Cathepsin S is a lysosomal cysteine protease of the papain family. It plays a major role in the processing of the MHC class II‑associated invariant chain and has been implicated in the pathogenesis of several diseases such as Alzheimer’s disease and degenerative disorders associated with the cells of the mononuclear phagocytic system. Human Cathepsin S is synthesized as a preproenzyme of 331 amino acid residues consisting of a signal peptide (residues 1‑16), a pro region (residues 17‑114), and the mature enzyme (residues 115‑331). Cathepsin S is less abundant in tissues than Cathepsins B, L, and H, with the highest levels found in lymph nodes, spleen, macrophages, and other phagocytic cells.
生物活性Immobilized Recombinant Human Cathepsin S protein (rp181600) at 1.0 μg/mL can bind Fsn0503h (anti-Cathepsin S) (Ab191933) with the EC50 of 30.8 ng/mL.
内毒素水平<1.0 EU/μg
表达系统HEK293
种属人(Human)
氨基酸1-331 aa
序列MKRLVCVLLVCSSAVAQLHKDPTLDHHWHLWKKTYGKQYKEKNEEAVRRLIWEKNLKFVMLHNLEHSMGMHSYDLGMNHLGDMTSEEVMSLMSSLRVPSQWQRNITYKSN
蛋白标签C-His
无载体Yes
无动物源Yes
Accession #P25774
来源重组表达
预测分子量38.3 kDa
SDS-PAGE36.4 kDa, under reducing conditions; 34.7 kDa, under non-reducing conditions.


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